PROSCILLARIDIN A
PROSCILLARIDIN A
CAS: 466-06-8
Molecular Formula: C30H42O8
PROSCILLARIDIN A - Names and Identifiers
PROSCILLARIDIN A - Physico-chemical Properties
| Molecular Formula | C30H42O8 |
| Molar Mass | 530.66 |
| Density | 1.33±0.1 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 233°C |
| Boling Point | 530.03°C (rough estimate) |
| Specific Rotation(α) | D20 -91.5° (CH3OH) |
| Solubility | Almost insoluble (0.039g/L) (25°C), |
| pKa | 13.01±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4900 (estimate) |
| In vitro study | Proscillaridin A (0-160 nM; 48 hours) reveals the antiproliferative response in a time- as well as dose-dependent manner in MCF-7 cells. |
PROSCILLARIDIN A - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | S28 - After contact with skin, wash immediately with plenty of soap-suds. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | UK6650000 |
| Toxicity | LD50 in male, female rats (mg/kg): 56, 76 orally (Goldenthal) |
PROSCILLARIDIN A - Reference Information
| biological activity | prosclilaridin A is A potent topoisomerase I and II topoisomerase I/II inhibitor, the IC50 values for inhibition of topoisomerase I and II were 30 nM and 100 nM, respectively. |
Last Update：2024-04-09 21:01:54
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